Projects - Social Science & Health Innovation for Tuberculosis

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Team members include Max R O'Donnell, Columbia University (PI); Nesri Padayatchi, CAPRISA (PI); Boitumelo Seepamore, University of KwaZulu-Natal; Amrita Daftary, York University; K Rivet Amico, University of Michigan; Jennifer Zelnick, Touro Graduate School of Social Work; Catherine Orrell, University of Cape Town; and Gerald Friedland, Yale University. [post_title] => Drug-resistant TB HIV Adherence Research [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => drug-resistant-tb-hiv-adherence-research [to_ping] => [pinged] => [post_modified] => 2021-03-16 20:54:08 [post_modified_gmt] => 2021-03-17 00:54:08 [post_content_filtered] => [post_parent] => 0 [guid] => http://sshiftb.org/?post_type=projects&p=1198 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 1518 [post_author] => 28 [post_date] => 2021-06-07 16:45:51 [post_date_gmt] => 2021-06-07 20:45:51 [post_content] => The delay among men in seeking healthcare for HIV and TB is well-documented. Men have been overlooked in TB research and, on the African continent, in health research more broadly, partly due to a view gender in TB and health research and interventions largely concerns women. We aimed to explore reasons for high levels of undiagnosed TB among men. We employed an exploratory research approach to highlight intersecting and multi-level influences at social/community and health system levels. Our team members included Jeremiah Chikovore, Human Sciences Research Council; Graham Hart, University College London; Geoff Chipungu, College of Medicine, Blantyre, Malawi; Nicola Desmond, Liverpool School of Tropical Medicine, and Elizabeth Corbett, London School of Hygiene and Tropical Medicine. [post_title] => Engaging Men in TB Control Interventions [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => engaging-men-in-tb-control-interventions [to_ping] => [pinged] => [post_modified] => 2021-06-07 16:45:51 [post_modified_gmt] => 2021-06-07 20:45:51 [post_content_filtered] => [post_parent] => 0 [guid] => https://sshiftb.org/?post_type=projects&p=1518 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 1707 [post_author] => 36 [post_date] => 2021-07-15 02:09:47 [post_date_gmt] => 2021-07-15 06:09:47 [post_content] => This study aims to build capacity in mHealth tuberculosis (TB) research and clinical trials with a focus on TB presumptive patients. Worldwide, national TB programs try to improve case detection rates and monitoring treatment outcomes, but little is known about the proportion of presumptive TB cases that never get tested for TB and the confirmed TB cases that never start treatment in endemic areas like Uganda, despite high prevalence and mortality rates. Uganda notified 43,736 total TB cases in 2015, of these only 53% received TB treatment. Patients can be lost to follow-up (LTFU) after being identified as presumptive TB cases and never get to test for TB or those who test and are confirmed to have TB, can also be lost and never start TB treatment. A systematic review found high levels of pre-treatment LTFU–ranging from 4 to 38%–,and was higher in sub-Saharan Africa (18%) compared to Asia (13%). Consequences of pre-diagnosis and pre-treatment LTFU are; untreated TB patients are infectious and can transmit TB to others and not starting TB treatment at all, causes high morbidity and mortality. Therefore, monitoring outcomes of presumptive TB patients is equally important as monitoring treatment outcomes. Short message service (SMS) and mobile money (MM) incentives have shown promise by improving health outcomes such as uptake of immunization, adherence to TB treatment, and ART. However, there is limited knowledge on whether text messages and MM incentives can increase linkage to care and treatment for presumptive TB patients in Uganda and sub-Saharan Africa. The aim of this study is to leverage SMS reminders and MM incentives in improving linkage to care of presumptive TB patients. We believe this will result in an increase in the proportion of presumptive TB patients that complete diagnosis and pre-treatment TB cases that link to care and treatment using SMS reminders and Mobile Money (MM) incentives. [post_title] => MILEAGE4TB: Using short message service reminders and mobile money incentives to enhance linkage to care of presumptive tuberculosis patients in uganda: a randomised controlled trial [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => mileage4tb-using-short-message-service-reminders-and-mobile-money-incentives-to-enhance-linkage-to-care-of-presumptive-tuberculosis-patients-in-uganda-a-randomised-controlled-trial [to_ping] => [pinged] => [post_modified] => 2021-07-15 02:09:47 [post_modified_gmt] => 2021-07-15 06:09:47 [post_content_filtered] => [post_parent] => 0 [guid] => https://sshiftb.org/?post_type=projects&p=1707 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 1139 [post_author] => 4 [post_date] => 2021-02-16 09:21:37 [post_date_gmt] => 2021-02-16 14:21:37 [post_content] => This study analyses aspects of values and preferences, acceptability and feasibility alongside a prospective study of Fujifilm SILVAMP TB (FujiLAM) and Omega CD4 point of care testing. [post_title] => Qualitative research and cost-effectiveness modelling of novel urine LAM assay in Malawi and Zambia [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => qualitative-research-and-cost-effectiveness-modelling-of-novel-urine-lam-assay-in-malawi-and-zambia-2 [to_ping] => [pinged] => [post_modified] => 2021-03-16 20:52:07 [post_modified_gmt] => 2021-03-17 00:52:07 [post_content_filtered] => [post_parent] => 0 [guid] => http://sshiftb.org/?post_type=projects&p=1139 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 1520 [post_author] => 19 [post_date] => 2021-05-28 14:55:34 [post_date_gmt] => 2021-05-28 18:55:34 [post_content] => The aim of this project is to analyse aspects of values and preferences, acceptability and feasibility alongside a prospective accuracy study of a novel TB diagnostic which requires urine as sample (Fujifilm SILVAMP TB (FujiLAM)), and Omega’s Visitect CD4 point of care testing, funded by DZIF. The project uses qualitative research alongside the trial in Malawi and Zambia. Project members include:

Claudia Denkinger (PI), Yannis Hermann, Federica Lainati, María del Mar Castro Noriega (University of Heidelberg)
Nora Engel (Maastricht University)
Chanda Mwamba (Centre for Infectious Disease Research in Zambia (CIDRZ))
Moses Kumwenda (Malawi-Liverpool-Wellcome Trust Clinical Research Programme)

[post_title] => Qualitative research of novel urine LAM assay in Malawi and Zambia to inform WHO policy [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => qualitative-research-of-novel-urine-lam-assay-in-malawi-and-zambia-to-inform-who-policy [to_ping] => [pinged] => [post_modified] => 2021-05-28 14:55:34 [post_modified_gmt] => 2021-05-28 18:55:34 [post_content_filtered] => [post_parent] => 0 [guid] => https://sshiftb.org/?post_type=projects&p=1520 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [5] => WP_Post Object ( [ID] => 1140 [post_author] => 4 [post_date] => 2021-02-16 09:27:17 [post_date_gmt] => 2021-02-16 14:27:17 [post_content] => Summary of study results: Managing patients requires 1) going beyond syndromic management based on vital signs and clinical indicators to recognising and intervening on health care-seeking related tensions to retain individuals in care, and 2) understanding and addressing TB stigma as it manifests and affects men and women differently in specific settings. [post_title] => TB and HIV stigma compounded by threatened masculinity: implications for TB health-care seeking in Malawi [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => tb-and-hiv-stigma-compounded-by-threatened-masculinity-implications-for-tb-health-care-seeking-in-malawi [to_ping] => [pinged] => [post_modified] => 2021-03-11 23:50:49 [post_modified_gmt] => 2021-03-12 04:50:49 [post_content_filtered] => [post_parent] => 0 [guid] => http://sshiftb.org/?post_type=projects&p=1140 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [6] => WP_Post Object ( [ID] => 1629 [post_author] => 38 [post_date] => 2021-06-18 19:01:40 [post_date_gmt] => 2021-06-18 23:01:40 [post_content] => Umoya omuhle is a three-year study that began in 2017 and uses a whole systems approach to look at infection prevention and control for drug-resistant tuberculosis in clinical settings of South Africa in an era of decentralised care. The name, Umoya omuhle, means good air in Zulu, and embodies the project vision of bringing a ‘breath of fresh air' to current thinking on infection prevention and control. The project is organised around a set of seven research questions looking at various aspects of TB infection prevention and control in healthcare facilities, with an aim to improve it. [post_title] => Umoya omuhle [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => umoya-omuhle [to_ping] => [pinged] => [post_modified] => 2021-06-18 19:01:40 [post_modified_gmt] => 2021-06-18 23:01:40 [post_content_filtered] => [post_parent] => 0 [guid] => https://sshiftb.org/?post_type=projects&p=1629 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [7] => WP_Post Object ( [ID] => 1616 [post_author] => 28 [post_date] => 2021-06-07 17:15:28 [post_date_gmt] => 2021-06-07 21:15:28 [post_content] => There is little research on the quality of care in the private sector, despite acknowledgment that a sizeable segment of the population (including those with TB-related symptoms) in high HIV and HIV/TB burden contexts make use of this sector. There is, furthermore, growing attention lately to how the private healthcare sector could be contributing to the 2.9 million people with TB who do not get diagnosed and subsequently get notified to official TB programmes. The project aimed to describe the quality of TB and HIV care among private general practitioners (GPs) in South Africa. Within a multi-technique study design woven around use of ‘Standardised patients’ - actors trained to systematically present a complaint or set of symptoms in real clinical settings - a qualitative sub-component sought insights into meanings and contexts surrounding private GPs’ management decisions. Team members included Amrita Daftary, York University; Sizulu Moyo, Human Sciences Research Council (HSRC); Madhukar Pai, McGill University; Jody Boffa, York University, and University of KwaZulu-Natal, and Jeremiah Chikovore, HSRC. [post_title] => Understanding the context of private general practitioners’ prescribing practices and patient management decisions in South Africa [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => understanding-the-context-of-private-general-practitioners-prescribing-practices-and-patient-management-decisions-in-south-africa [to_ping] => [pinged] => [post_modified] => 2021-06-07 17:21:17 [post_modified_gmt] => 2021-06-07 21:21:17 [post_content_filtered] => [post_parent] => 0 [guid] => http://sshiftb.org/?post_type=projects&p=1616 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 8 [current_post] => -1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 1198 [post_author] => 5 [post_date] => 2021-03-02 12:34:54 [post_date_gmt] => 2021-03-02 17:34:54 [post_content] => Social science qualitative research supporting the design, implementation and evaluation of multi-modal interventions within clinical RCTs aimed to improve treatment adherence and retention in care among people with drug-resistant TB and HIV in KwaZulu-Natal, South Africa. Team members include Max R O'Donnell, Columbia University (PI); Nesri Padayatchi, CAPRISA (PI); Boitumelo Seepamore, University of KwaZulu-Natal; Amrita Daftary, York University; K Rivet Amico, University of Michigan; Jennifer Zelnick, Touro Graduate School of Social Work; Catherine Orrell, University of Cape Town; and Gerald Friedland, Yale University. [post_title] => Drug-resistant TB HIV Adherence Research [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => drug-resistant-tb-hiv-adherence-research [to_ping] => [pinged] => [post_modified] => 2021-03-16 20:54:08 [post_modified_gmt] => 2021-03-17 00:54:08 [post_content_filtered] => [post_parent] => 0 [guid] => http://sshiftb.org/?post_type=projects&p=1198 [menu_order] => 0 [post_type] => projects [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 8 [max_num_pages] => 1 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => 1 [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => 1 [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => 1 [query_vars_hash:WP_Query:private] => 9ea6badca7278e0130d7c9c41c652c1b [query_vars_changed:WP_Query:private] => 1 [thumbnails_cached] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )

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Here are some exciting projects and endeavours that represent social science work in TB, undertaken by contributors to SSHIFTB.

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Drug-resistant TB HIV Adherence Research

Social science qualitative research supporting the design, implementation and evaluation of multi-modal interventions within clinical RCTs aimed to improve treatment adherence and retention in care among people with drug-resistant TB [ ... ]

Engaging Men in TB Control Interventions

The delay among men in seeking healthcare for HIV and TB is well-documented. Men have been overlooked in TB research and, on the African continent, in health research more broadly, [ ... ]

MILEAGE4TB: Using short message service reminders and mobile money incentives to enhance linkage to care of presumptive tuberculosis patients in uganda: a randomised controlled trial

This study aims to build capacity in mHealth tuberculosis (TB) research and clinical trials with a focus on TB presumptive patients. Worldwide, national TB programs try to improve case detection [ ... ]

Qualitative research and cost-effectiveness modelling of novel urine LAM assay in Malawi and Zambia

This study analyses aspects of values and preferences, acceptability and feasibility alongside a prospective study of Fujifilm SILVAMP TB (FujiLAM) and Omega CD4 point of care testing.

Qualitative research of novel urine LAM assay in Malawi and Zambia to inform WHO policy

The aim of this project is to analyse aspects of values and preferences, acceptability and feasibility alongside a prospective accuracy study of a novel TB diagnostic which requires urine as [ ... ]

TB and HIV stigma compounded by threatened masculinity: implications for TB health-care seeking in Malawi

Summary of study results: Managing patients requires 1) going beyond syndromic management based on vital signs and clinical indicators to recognising and intervening on health care-seeking related tensions to retain [ ... ]

Umoya omuhle

Umoya omuhle is a three-year study that began in 2017 and uses a whole systems approach to look at infection prevention and control for drug-resistant tuberculosis in clinical settings of [ ... ]

Understanding the context of private general practitioners’ prescribing practices and patient management decisions in South Africa

There is little research on the quality of care in the private sector, despite acknowledgment that a sizeable segment of the population (including those with TB-related symptoms) in high HIV [ ... ]