Mphothulo, N., & Loveday, M. (2026). Designing and evaluating the acceptability of a psychosocial and socioeconomic support package for people with drug-resistant tuberculosis in Johannesburg, South Africa. PloS one, 21(3), e0343154. https://doi.org/10.1371/journal.pone.0343154


Summary

Drug-resistant tuberculosis (DR-TB) is a global health problem that presents multifaceted challenges to people living with the disease. These challenges lead to sub-optimal adherence in some DR-TB patients who are then not cured of their TB. Besides the challenges associated with taking treatment, many patients with DR-TB also have to contend with psychosocial and socioeconomic challenges. The objective of this study was to develop a psychosocial and socioeconomic intervention for people with DR-TB in Johannesburg, South Africa, and evaluate if they find it acceptable. Guided by the Behaviour Change Wheel (BCW) and Perceptions and Practicalities Approach (PaPA) frameworks, and utilising a participatory research approach, We developed a support package with input from a qualitative needs assessment with DR-TB patients (n = 16) and family members (n = 8) and input from various stakeholders (n = 18), (health managers, clinicians and officials from social security departments). The support package was then evaluated for acceptability by patients who had successfully completed DR-TB treatment (n = 13) and their families (n = 6), using an exploratory qualitative method. Both successfully treated DR-TB patients and their family members found the intervention to be acceptable and believed it will reduce the barriers to retention in care that they faced during their treatment journey.

Geographies
South Africa

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